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DUHS Clinical Molecular Diagnostics

        The Clinical Molecular Diagnostics Laboratory at Duke University Health Systems is a College of American Pathologist (CAP) accredited, CLIA certified, state of the art, multidisciplinary laboratory that is dedicated to providing patients and physicians with comprehensive and accurate molecular testing. Our laboratory provides a wide range of DNA and RNA based tests for inherited genetic diseases, hematologic malignancies and infectious diseases all of which are performed at the Duke University Health System Consolidated Laboratories on the Duke University Hospital Campus.

Areas of Expertise

      One of our primary strengths is molecular testing of lymphomas and leukemias. In this regard, we work closely with other DUHS Molecular Pathology laboratories including the Clinical Cytogenetics, Flow Cytometry, and Immunohistochemistry laboratories to provide an integrated approach to detecting disease-specific diagnostic and prognostic molecular markers. We are constantly expanding this coordinated approach to develop the most advanced and clinically useful assays for our Duke lymphoma and leukemia patients.

      Our second major strength is molecular testing in medical genetics. We routinely perform a number of DNA based tests for both diagnostic evaluation and carrier screening for inherited genetic diseases. These studies are also performed in close coordination with our Cytogenetics Laboratory to provide an integrated service to our patients and physician clients.
Translational Medicine

     One of the missions of the DUHS Clinical Molecular Diagnostics laboratory is to serve as the outlet for true translational research for our Duke University Medical Center scientists.  To this end, our laboratory has a dedicated group of test development technologists, scientists and physicians to bring discoveries from the bench top to the bed side.

Contact Us

     We are always available to answer your questions. Please contact us for more information about our services or for help understanding the results of your molecular diagnostic tests.

     Details about all of the tests performed by the Molecular Diagnostics Laboratory can be found here: Test Catalog: MDx

How to Request Testing from the DUHS Clinical Molecular Diagnostics Laboratory

Requests for testing from our laboratory can be made by a US licensed physician on behalf of their patient. If you are a physician and have not used the services of our laboratory previously or if you are a physician whose practice is outside of the Duke University Health System, please contact us. For Duke providers, please use electronic order entry through our Epic LIS

Test Request Forms

We have three different test request forms. If you are unsure which is the correct form to use, please contact the laboratory. Be as complete as possible when filling out these forms. If your patient is within the Duke system and you are a Duke physician please use the electronic order entry system in Epic. If you are a physician outside of the DUHS system please contact the laboratory if you are unsure which form to complete or if you need additional information.

General Test Requisition Form General Test Requisition Form. This is for DUHS internal clients only.
Medical Genetics Requisition Form Medical Genetics Requisition Form. This for is for external (Non-DUHS) physicians.

Informed Consent

For some tests, patient informed consent is required. Informed consent requirements are noted on the test requisition forms. Informed consent is the responsibility of the ordering physician. We do not have separate consent forms for patients. No testing will be performed without a physician of record who is able to consent their patient. In addition, results are sent to the ordering physician, not to the patient directly. This gives the ordering physician an opportunity to explain the results of testing. If you need help with informed consent or with the interpretation of test results, please contact the laboratory.

Contact Us

(919) 684-2698
Wadsworth Bldg, Rm 0220, 2351 Erwin Rd
Durham, NC, 27705
Phone: 919-684-2698 | Fax: 919-668-9173
CLIA Director: Michael Datto MD PhD (CLIA: 34D0696636)

Our Leadership Team

Jennifer Sanks MT(ASCP), MB(ASCP)
Laboratory Manager
Michael Datto MD, PhD
Siby Sebastian PhD, DABMG
Associate Director
Catherine Rehder PhD, FACMG
Associate Director
Kristen Deak PhD, FACMG
Assistant Director